Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

Cyclodipeptide synthases (CDPSs) can catalyze the formation of two successive peptide bonds by hijacking aminoacyl-tRNAs from the ribosomal machinery resulting in diketopiperazines (DKPs). Here, three CDPS-containing loci (dmt1–3) are discovered by genome mining and comparative genome analysis of St...

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Detalles Bibliográficos
Autores principales: Yao, Tingting, Liu, Jing, Liu, Zengzhi, Li, Tong, Li, Huayue, Che, Qian, Zhu, Tianjiao, Li, Dehai, Gu, Qianqun, Li, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173783/
https://www.ncbi.nlm.nih.gov/pubmed/30291234
http://dx.doi.org/10.1038/s41467-018-06411-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173783/
https://www.ncbi.nlm.nih.gov/pubmed/30291234
http://dx.doi.org/10.1038/s41467-018-06411-x

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