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A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS

BACKGROUND: Neoadjuvant chemotherapy (NAC) allows earlier treatment of rectal cancer micro-metastases but is not standard of care. There are currently no biomarkers predicting long-term progression-free survival (PFS) benefit from NAC. PATIENTS AND METHODS: In this single arm phase II trial, patient...

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Detalles Bibliográficos
Autores principales: Gollins, Simon, West, Nicholas, Sebag-Montefiore, David, Susnerwala, Shabbir, Falk, Stephen, Brown, Nick, Saunders, Mark, Quirke, Philip, Ray, Ruby, Parsons, Philip, Griffiths, Gareth, Maughan, Tim, Adams, Richard, Hurt, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173784/
https://www.ncbi.nlm.nih.gov/pubmed/30116024
http://dx.doi.org/10.1038/s41416-018-0209-4