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Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation

BACKGROUND: Although pharmacological treatment has increased the average life expectancy of patients with cystic fibrosis, the median survival of females is shorter than that of males. In vitro and in vivo studies have shown that estrogens play a relevant role in the disease progression. The aim of...

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Detalles Bibliográficos
Autores principales: Imberti, Roberto, Garavaglia, Maria Lisa, Verduci, Ivan, Cannavale, Gaetano, Balduzzi, Giorgio, Papetti, Sara, Mazzanti, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173901/
https://www.ncbi.nlm.nih.gov/pubmed/30290809
http://dx.doi.org/10.1186/s12931-018-0901-1