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Clinical significance in pediatric oncology randomized controlled treatment trials: a systematic review
BACKGROUND: Clinical significance in a randomized controlled trial (RCT) can be determined using the minimal clinically important difference (MCID), which should inform the delta value used to determine sample size. The primary objective was to assess clinical significance in the pediatric oncology...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173909/ https://www.ncbi.nlm.nih.gov/pubmed/30290839 http://dx.doi.org/10.1186/s13063-018-2925-8 |