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Rapid and efficient production of cecropin A antibacterial peptide in Escherichia coli by fusion with a self-aggregating protein

BACKGROUND: Cecropin A (CeA), a natural cationic antimicrobial peptide, exerts potent antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, making it an attractive candidate substitute for antimicrobials. However, the low production rate and cumbersome, expensi...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Zheng, Kaiwen, Lin, Jinglian, Huang, Minhua, Ma, Yi, Li, Shan, Luo, Xiaochun, Wang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173929/
https://www.ncbi.nlm.nih.gov/pubmed/30290795
http://dx.doi.org/10.1186/s12896-018-0473-7