Structural basis of the filamin A actin-binding domain interaction with F-actin

Actin-crosslinking proteins assemble actin filaments into higher-order structures essential for orchestrating cell shape, adhesion and motility. Missense mutations in the tandem calponin homology (CH) domains of their actin-binding domains (ABDs) underlie numerous genetic diseases, but a molecular u...

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Detalles Bibliográficos
Autores principales: Iwamoto, Daniel V., Huehn, Andrew, Simon, Bertrand, Huet-Calderwood, Clotilde, Baldassarre, Massimiliano, Sindelar, Charles V., Calderwood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173970/
https://www.ncbi.nlm.nih.gov/pubmed/30224736
http://dx.doi.org/10.1038/s41594-018-0128-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173970/
https://www.ncbi.nlm.nih.gov/pubmed/30224736
http://dx.doi.org/10.1038/s41594-018-0128-3

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