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Structural basis of the filamin A actin-binding domain interaction with F-actin

Actin-crosslinking proteins assemble actin filaments into higher-order structures essential for orchestrating cell shape, adhesion and motility. Missense mutations in the tandem calponin homology (CH) domains of their actin-binding domains (ABDs) underlie numerous genetic diseases, but a molecular u...

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Detalles Bibliográficos
Autores principales:	Iwamoto, Daniel V., Huehn, Andrew, Simon, Bertrand, Huet-Calderwood, Clotilde, Baldassarre, Massimiliano, Sindelar, Charles V., Calderwood, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173970/ https://www.ncbi.nlm.nih.gov/pubmed/30224736 http://dx.doi.org/10.1038/s41594-018-0128-3

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