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Alternative Splicing Rewires Hippo Signaling Pathway in Hepatocytes to Promote Liver Regeneration
During liver regeneration, most new hepatocytes arise via self-duplication; yet, the underlying mechanisms that drive hepatocyte proliferation following injury remain poorly defined. By combining high-resolution transcriptome- and polysome-profiling of hepatocytes purified from quiescent and toxin-i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173981/ https://www.ncbi.nlm.nih.gov/pubmed/30250226 http://dx.doi.org/10.1038/s41594-018-0129-2 |