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Phosphatidylserine Externalization Results from and Causes Neurite Degeneration in Drosophila

Phagocytic clearance of degenerating dendrites or axons is critical for maintaining tissue homeostasis and preventing neuroinflammation. Externalized phosphatidylserine (PS) has been postulated to be an ‘‘eat-me’’ signal allowing recognition of degenerating neurites by phagocytes. Here we show that...

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Detalles Bibliográficos
Autores principales: Sapar, Maria L., Ji, Hui, Wang, Bei, Poe, Amy R., Dubey, Kush, Ren, Xingjie, Ni, Jian-Quan, Han, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174084/
https://www.ncbi.nlm.nih.gov/pubmed/30157423
http://dx.doi.org/10.1016/j.celrep.2018.07.095