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First Degree Relatives of Patients with Celiac Disease Harbour an Intestinal Transcriptomic Signature that Might Protect them from Enterocyte Damage

INTRODUCTION: Celiac disease (CeD) is an autoimmune enteropathy which affects approximately 0.7% of the global population. While first-degree relatives (FDR) of patients with CeD have a 7.5% risk of developing enteropathy, many remain protected. Therefore, intestinal mucosa of FDR might have protect...

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Detalles Bibliográficos
Autores principales: Acharya, Pragyan, Kutum, Rintu, Pandey, Rajesh, Mishra, Asha, Saha, Rohini, Munjal, Akshay, Ahuja, Vineet, Mukerji, Mitali, Makharia, Govind K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174158/
https://www.ncbi.nlm.nih.gov/pubmed/30293993
http://dx.doi.org/10.1038/s41424-018-0059-7