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Transmembrane TM3b of Mechanosensitive Channel MscS Interacts With Cytoplasmic Domain Cyto-Helix

The mechanosensitive channel MscS functions as an osmolyte emergency release-valve in the event of a sudden decrease in external environmental osmolarity. MscS has served as a paradigm for studying how channel proteins detect and respond to mechanical stimuli. However, the inter-domain interactions...

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Detalles Bibliográficos
Autores principales: Wang, Xiaomin, Tang, Siyang, Wen, Xiaoxu, Hong, Lang, Hong, Feifan, Li, Yuezhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174206/
https://www.ncbi.nlm.nih.gov/pubmed/30327617
http://dx.doi.org/10.3389/fphys.2018.01389