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PD-L1(+) Regulatory B Cells Are Significantly Decreased in Rheumatoid Arthritis Patients and Increase After Successful Treatment

Background: B cells play an important role in the development and maintenance of rheumatoid arthritis (RA). Although IL-10–producing B cells represent a major subset of regulatory B cells (Bregs) able to suppress autoimmune and inflammatory responses, recent reports showed that B cell-mediated immun...

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Detalles Bibliográficos
Autores principales: Zacca, Estefanía R., Onofrio, Luisina I., Acosta, Cristina D. V., Ferrero, Paola V., Alonso, Sergio M., Ramello, María C., Mussano, Eduardo, Onetti, Laura, Cadile, Isaac I., Stancich, Maria I., Taboada Bonfanti, Maria C., Montes, Carolina L., Acosta Rodríguez, Eva V., Gruppi, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174216/
https://www.ncbi.nlm.nih.gov/pubmed/30327652
http://dx.doi.org/10.3389/fimmu.2018.02241