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The Relationship Between Population Attributable Fraction and Heritability in Genetic Studies

Population attributable fraction (PAF) has been widely used to quantify the proportion of disease risk in a population that can be attributed to risk factors in epidemiological studies. However, the use of PAF has been limited in assessing the contribution of genetic variants. Most notably, the PAF...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wang, Tao, Hosgood, H. Dean, Lan, Qing, Xue, Xiaonan
التنسيق: Online مقال نص
اللغة:English
منشور في: Frontiers Media S.A. 2018
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174220/
https://www.ncbi.nlm.nih.gov/pubmed/30327663
http://dx.doi.org/10.3389/fgene.2018.00352