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A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease

PURPOSE: The aim of this study was to evaluate the safety and efficacy of OTX-101, a clear nanomicellar aqueous solution of cyclosporine, in the treatment of dry eye disease (DED). PATIENTS AND METHODS: This was a 12-week multicenter, randomized, prospective, double-masked, vehicle-controlled, dose-...

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Detalles Bibliográficos
Autores principales: Tauber, Joseph, Schechter, Barry A, Bacharach, Jason, Toyos, Melissa M, Smyth-Medina, Robert, Weiss, Sidney L, Luchs, Jodi I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174300/
https://www.ncbi.nlm.nih.gov/pubmed/30323548
http://dx.doi.org/10.2147/OPTH.S175065