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Fasudil, a Rho-Kinase Inhibitor, Exerts Cardioprotective Function in Animal Models of Myocardial Ischemia/Reperfusion Injury: A Meta-Analysis and Review of Preclinical Evidence and Possible Mechanisms

Fasudil, a Rho-kinase inhibitor, has shown outstanding therapeutic effects against cerebral vasospasm after subarachnoid hemorrhage (SAH) in humans. Studies show various biological effects of fasudil in the cardiovascular system. We conducted a preclinical systematic review to determine the efficacy...

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Detalles Bibliográficos
Autores principales: Huang, Yue-yue, Wu, Jian-ming, Su, Tong, Zhang, Song-yue, Lin, Xiao-ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174418/
https://www.ncbi.nlm.nih.gov/pubmed/30327600
http://dx.doi.org/10.3389/fphar.2018.01083