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POxylated Dendrimer‐Based Nano‐in‐Micro Dry Powder Formulations for Inhalation Chemotherapy

POxylated polyurea dendrimer (PURE(G4)OOx(48))‐based nanoparticles were loaded with paclitaxel (PTX) and doxorubicin (DOX) and micronized with chitosan (CHT) by using supercritical CO(2)‐assisted spray drying (SASD). Respirable, biocompatible, and biodegradable dry powder formulations (DPFs) were pr...

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Detalles Bibliográficos
Autores principales: Restani, Rita B., Pires, Rita F., Tolmatcheva, Anna, Cabral, Rita, Baptista, Pedro V., Fernandes, Alexandra R., Casimiro, Teresa, Bonifácio, Vasco D. B., Aguiar‐Ricardo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174550/
https://www.ncbi.nlm.nih.gov/pubmed/30338202
http://dx.doi.org/10.1002/open.201800093