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Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study

BACKGROUND: The continuing morbidity and mortality associated with infection with malaria parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in clinical trials in malaria-endemic areas has thus far been disappointing, sparking renewed interest in the whole p...

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Detalles Bibliográficos
Autores principales: Stanisic, Danielle I., Fink, James, Mayer, Johanna, Coghill, Sarah, Gore, Letitia, Liu, Xue Q., El-Deeb, Ibrahim, Rodriguez, Ingrid B., Powell, Jessica, Willemsen, Nicole M., De, Sai Lata, Ho, Mei-Fong, Hoffman, Stephen L., Gerrard, John, Good, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174572/
https://www.ncbi.nlm.nih.gov/pubmed/30293531
http://dx.doi.org/10.1186/s12916-018-1173-9