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Improving the Reliability and Utility of Streptozotocin-Induced Rat Diabetic Model

The Streptozotocin- (STZ-) induced diabetic model is widely used; however, unexplained acute toxicity has given the model an unreliable reputation. To improve the reliability and utility of this model, we characterize the age dependence of STZ toxicity and introduce novel endpoints to assess diabeti...

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Detalles Bibliográficos
Autores principales: Wang-Fischer, Yanlin, Garyantes, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174751/
https://www.ncbi.nlm.nih.gov/pubmed/30345315
http://dx.doi.org/10.1155/2018/8054073