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Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion

In patients with diabetes mellitus (DM), impairments of circadian rhythms, including the sleep–wake cycle, blood pressure, and plasma melatonin concentrations, are frequently observed. Animal models of DM are also reported to show aberrant circadian rhythms. However, the changes in the circadian rhy...

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Detalles Bibliográficos
Autores principales: Sakimura, Katsuya, Maekawa, Tatsuya, Kume, Shin-ichi, Ohta, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174757/
https://www.ncbi.nlm.nih.gov/pubmed/30344606
http://dx.doi.org/10.1155/2018/9065690