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The enzyme activity of histone deacetylase 8 is modulated by a redox-switch
Enzymes from the histone deacetylase (HDAC) family are highly regulated by different mechanisms. However, only very limited knowledge exists about the regulation of HDAC8, an established target in multiple types of cancer. A previous dedicated study of HDAC class I enzymes identified no redox-sensit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174833/ https://www.ncbi.nlm.nih.gov/pubmed/30292946 http://dx.doi.org/10.1016/j.redox.2018.09.013 |