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Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis
Endothelial dysfunction induced by hyperhomocysteinemia (HHcy) plays a critical role in vascular pathology. However, little is known about the role of endoplasmic reticulum (ER) redox homeostasis in HHcy-induced endothelial dysfunction. Here, we show that Hcy induces ER oxidoreductin-1α (Ero1α) expr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174864/ https://www.ncbi.nlm.nih.gov/pubmed/30292945 http://dx.doi.org/10.1016/j.redox.2018.09.021 |