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Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease

Severe and recurrent cisplatin-induced acute kidney injury (AKI) as part of standard cancer therapy is a known risk factor for development of chronic kidney disease (CKD). The specific role of superoxide (O(2)(•-))-mediated disruption of mitochondrial oxidative metabolism in CKD after cisplatin trea...

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Detalles Bibliográficos
Autores principales: Mapuskar, Kranti A., Wen, Hsiang, Holanda, Danniele G., Rastogi, Prerna, Steinbach, Emily, Han, Rachel, Coleman, Mitchell C., Attanasio, Massimo, Riley, Dennis P., Spitz, Douglas R., Allen, Bryan G., Zepeda-Orozco, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174865/
https://www.ncbi.nlm.nih.gov/pubmed/30296702
http://dx.doi.org/10.1016/j.redox.2018.09.020