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Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease
Severe and recurrent cisplatin-induced acute kidney injury (AKI) as part of standard cancer therapy is a known risk factor for development of chronic kidney disease (CKD). The specific role of superoxide (O(2)(•-))-mediated disruption of mitochondrial oxidative metabolism in CKD after cisplatin trea...
Autores principales: | Mapuskar, Kranti A., Wen, Hsiang, Holanda, Danniele G., Rastogi, Prerna, Steinbach, Emily, Han, Rachel, Coleman, Mitchell C., Attanasio, Massimo, Riley, Dennis P., Spitz, Douglas R., Allen, Bryan G., Zepeda-Orozco, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174865/ https://www.ncbi.nlm.nih.gov/pubmed/30296702 http://dx.doi.org/10.1016/j.redox.2018.09.020 |
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