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Influence of mutation bias and hydrophobicity on the substitution rates and sequence entropies of protein evolution
The number of amino acids that occupy a given protein site during evolution reflects the selective constraints operating on the site. This evolutionary variability is strongly influenced by the structural properties of the site in the native structure, and it is quantified either through sequence en...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174885/ https://www.ncbi.nlm.nih.gov/pubmed/30310736 http://dx.doi.org/10.7717/peerj.5549 |