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Personalization of medicine requires better observational evidence

Evidence-based medicine has become associated with a preference for randomized trials. Randomization is a powerful tool against both known and unknown confounding. However, due to cost-induced constraints in size, randomized trials are seldom able to provide the subgroup analyses needed to gain much...

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Detalles Bibliográficos
Autores principales: Middelburg, Rutger A, Arbous, M Sesmu, Middelburg, Judith G, van der Bom, Johanna G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174902/
https://www.ncbi.nlm.nih.gov/pubmed/30323682
http://dx.doi.org/10.2147/CLEP.S167137