The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties

The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in prostate, blood, and bone cancer. The ERG gene is alternatively spliced; of particular interest is its cassette exon 7b which adds 24 amino acids, in frame, to the transcript...

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Detalles Bibliográficos
Autores principales: Jumbe, Samantha L., Porazinski, Sean R., Oltean, Sebastian, Mansell, Jason P., Vahabi, Bahareh, Wilson, Ian D., Ladomery, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174920/
https://www.ncbi.nlm.nih.gov/pubmed/30296658
http://dx.doi.org/10.1016/j.tranon.2018.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174920/
https://www.ncbi.nlm.nih.gov/pubmed/30296658
http://dx.doi.org/10.1016/j.tranon.2018.09.001

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