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A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones

Enzymatic core components from trans‐acyltransferase polyketide synthases (trans‐AT PKSs) catalyze exceptionally diverse biosynthetic transformations to generate structurally complex bioactive compounds. Here we focus on a group of oxygenases identified in various trans‐AT PKS pathways, including th...

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Detalles Bibliográficos
Autores principales: Meoded, Roy A., Ueoka, Reiko, Helfrich, Eric J. N., Jensen, Katja, Magnus, Nancy, Piechulla, Birgit, Piel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174933/
https://www.ncbi.nlm.nih.gov/pubmed/29898240
http://dx.doi.org/10.1002/anie.201805363