Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2

Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) and Kupffer cells (KCs) leads to liver fibrosis. Here, we aimed to investigate the molecular mechanism and define the cell type involved in mediating the sphingosine kinase (SphK)1‐dependent effect on liver fibrosis. The l...

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Detalles Bibliográficos
Autores principales: Lan, Tian, Li, Changzheng, Yang, Guizhi, Sun, Yue, Zhuang, Lihang, Ou, Yitao, Li, Hui, Wang, Genshu, Kisseleva, Tatiana, Brenner, David, Guo, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174945/
https://www.ncbi.nlm.nih.gov/pubmed/29572892
http://dx.doi.org/10.1002/hep.29885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174945/
https://www.ncbi.nlm.nih.gov/pubmed/29572892
http://dx.doi.org/10.1002/hep.29885

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