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Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2
Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) and Kupffer cells (KCs) leads to liver fibrosis. Here, we aimed to investigate the molecular mechanism and define the cell type involved in mediating the sphingosine kinase (SphK)1‐dependent effect on liver fibrosis. The l...
Autores principales: | Lan, Tian, Li, Changzheng, Yang, Guizhi, Sun, Yue, Zhuang, Lihang, Ou, Yitao, Li, Hui, Wang, Genshu, Kisseleva, Tatiana, Brenner, David, Guo, Jiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174945/ https://www.ncbi.nlm.nih.gov/pubmed/29572892 http://dx.doi.org/10.1002/hep.29885 |
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