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Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain

Mice lacking the epidermal growth factor receptor (EGFR) develop an early postnatal degeneration of the frontal cortex and olfactory bulbs and show increased cortical astrocyte apoptosis. The poor health and early lethality of EGFR(−/−) mice prevented the analysis of mechanisms responsible for the n...

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Detalles Bibliográficos
Autores principales: Robson, Jonathan P., Wagner, Bettina, Glitzner, Elisabeth, Heppner, Frank L., Steinkellner, Thomas, Khan, Deeba, Petritsch, Claudia, Pollak, Daniela D., Sitte, Harald H., Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174950/
https://www.ncbi.nlm.nih.gov/pubmed/30028091
http://dx.doi.org/10.1111/febs.14603