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Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain
Mice lacking the epidermal growth factor receptor (EGFR) develop an early postnatal degeneration of the frontal cortex and olfactory bulbs and show increased cortical astrocyte apoptosis. The poor health and early lethality of EGFR(−/−) mice prevented the analysis of mechanisms responsible for the n...
Autores principales: | Robson, Jonathan P., Wagner, Bettina, Glitzner, Elisabeth, Heppner, Frank L., Steinkellner, Thomas, Khan, Deeba, Petritsch, Claudia, Pollak, Daniela D., Sitte, Harald H., Sibilia, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174950/ https://www.ncbi.nlm.nih.gov/pubmed/30028091 http://dx.doi.org/10.1111/febs.14603 |
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