Expansion of the Substrate Specificity of Porcine Kidney D‐Amino Acid Oxidase for S‐Stereoselective Oxidation of 4‐Cl‐Benzhydrylamine

Discovery and development of enzymes for the synthesis of chiral amines have been a hot topic for basic and applied aspects of biocatalysts. Based on our X‐ray crystallographic analyses of porcine kidney D‐amino acid oxidase (pkDAO) and its variants, we rationally designed a new variant that catalyz...

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Detalles Bibliográficos
Autores principales: Yasukawa, Kazuyuki, Motojima, Fumihiro, Ono, Atsushi, Asano, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174955/
https://www.ncbi.nlm.nih.gov/pubmed/30333894
http://dx.doi.org/10.1002/cctc.201800614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174955/
https://www.ncbi.nlm.nih.gov/pubmed/30333894
http://dx.doi.org/10.1002/cctc.201800614

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