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Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target

Malignant melanoma of the conjunctiva (CM) is an uncommon but potentially deadly disorder. Many malignancies show an increased activity of the epigenetic modifier enhancer of zeste homolog 2 (EZH2). We studied whether EZH2 is expressed in CM, and whether it may be a target for therapy in this malign...

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Detalles Bibliográficos
Autores principales: Cao, Jinfeng, Pontes, Kelly CS, Heijkants, Renier C, Brouwer, Niels J, Groenewoud, Arwin, Jordanova, Ekaterina S, Marinkovic, Marina, van Duinen, Sjoerd, Teunisse, Amina FAS, Verdijk, Robert M, Snaar‐Jagalska, Ewa, Jochemsen, Aart G, Jager, Martine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174981/
https://www.ncbi.nlm.nih.gov/pubmed/29732557
http://dx.doi.org/10.1002/path.5094