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A protein chimera strategy supports production of a model “difficult‐to‐express” recombinant target

Due in part to the needs of the biopharmaceutical industry, there has been an increased drive to generate high quality recombinant proteins in large amounts. However, achieving high yields can be a challenge as the novelty and increased complexity of new targets often makes them ‘difficult‐to‐expres...

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Detalles Bibliográficos
Autores principales: Hussain, Hirra, Fisher, David I., Roth, Robert G., Mark Abbott, W., Carballo‐Amador, Manuel Alejandro, Warwicker, Jim, Dickson, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174982/
https://www.ncbi.nlm.nih.gov/pubmed/29933498
http://dx.doi.org/10.1002/1873-3468.13170