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T‐cell egress from the thymus: Should I stay or should I go?

T‐cells bearing the αβTCR play a vital role in defending the host against foreign pathogens and malignant transformation of self. Importantly, T‐cells are required to remain tolerant to the host's own cells and tissues in order to prevent self‐reactive responses that can lead to autoimmune dise...

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Detalles Bibliográficos
Autores principales: James, Kieran D., Jenkinson, William E., Anderson, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174998/
https://www.ncbi.nlm.nih.gov/pubmed/29485734
http://dx.doi.org/10.1002/JLB.1MR1217-496R