Point estimation following two‐stage adaptive threshold enrichment clinical trials

Recently, several study designs incorporating treatment effect assessment in biomarker‐based subpopulations have been proposed. Most statistical methodologies for such designs focus on the control of type I error rate and power. In this paper, we have developed point estimators for clinical trials t...

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Detalles Bibliográficos
Autores principales: Kimani, Peter K., Todd, Susan, Renfro, Lindsay A., Stallard, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175016/
https://www.ncbi.nlm.nih.gov/pubmed/29855066
http://dx.doi.org/10.1002/sim.7831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175016/
https://www.ncbi.nlm.nih.gov/pubmed/29855066
http://dx.doi.org/10.1002/sim.7831

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