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Cell line-based xenograft mouse model of paediatric glioma stem cells mirrors the clinical course of the patient
The leading cause of cancer-related mortality among children is brain tumour, and glioblastoma multiforme (GBM) has the worst prognosis. New treatments are urgently needed, but with few cases and clinical trials in children, pre-clinical models such as patient-derived tumour xenografts (PDTX) are im...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175027/ https://www.ncbi.nlm.nih.gov/pubmed/29982329 http://dx.doi.org/10.1093/carcin/bgy091 |