Cargando…

Bioavailability of Glucoraphanin and Sulforaphane from High‐Glucoraphanin Broccoli

SCOPE: Broccoli accumulates 4‐methylsulphinylbutyl glucosinolate (glucoraphanin) which is hydrolyzed to the isothiocyanate sulforaphane. Through the introgression of novel alleles of the Myb28 transcription factor from Brassica villosa, broccoli genotypes have been developed that have enhanced level...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sivapalan, Tharsini, Melchini, Antonietta, Saha, Shikha, Needs, Paul W., Traka, Maria H., Tapp, Henri, Dainty, Jack R., Mithen, Richard F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175108/ https://www.ncbi.nlm.nih.gov/pubmed/29266773 http://dx.doi.org/10.1002/mnfr.201700911

Ejemplares similares

Genetic regulation of glucoraphanin accumulation in Beneforté® broccoli
por: Traka, Maria H, et al.
Publicado: (2013)

Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase
por: Fahey, Jed W., et al.
Publicado: (2015)

Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials
por: Armah, Charlotte N, et al.
Publicado: (2015)

Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial
por: Traka, Maria H, et al.
Publicado: (2019)

A diet rich in high-glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles by modulating mitochondrial function(1)(2)(3)
por: Armah, Charlotte N, et al.
Publicado: (2013)

An LC-MS/MS Method to Measure S-Methyl-l-Cysteine and S-Methyl-l-Cysteine Sulfoxide in Human Specimens Using Isotope Labelled Internal Standards
por: Sivapalan, Tharsini, et al.
Publicado: (2019)

Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration
por: Fahey, Jed W., et al.
Publicado: (2019)

Accumulation of Dietary S‐Methyl Cysteine Sulfoxide in Human Prostate Tissue
por: Coode‐Bate, Jack, et al.
Publicado: (2019)

Dietary Broccoli Alters Rat Cecal Microbiota to Improve Glucoraphanin Hydrolysis to Bioactive Isothiocyanates
por: Liu, Xiaoji, et al.
Publicado: (2017)

Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforaphane
por: Abukhabta, Salah, et al.
Publicado: (2020)

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases
por: Bousquet, Jean, et al.
Publicado: (2020)

Glucoraphanin and sulforaphane biosynthesis by melatonin mediating nitric oxide in hairy roots of broccoli (Brassica oleracea L. var. italica Planch): insights from transcriptome data
por: Ma, Shaoying, et al.
Publicado: (2022)

Influence of sequential exogenous pretreatment and contact ultrasound-assisted air drying on the metabolic pathway of glucoraphanin in broccoli florets
por: Liu, Beini, et al.
Publicado: (2022)

Optimization of Engineered Production of the Glucoraphanin Precursor Dihomomethionine in Nicotiana benthamiana
por: Crocoll, Christoph, et al.
Publicado: (2016)

Accumulation of Palmitoylcarnitine and Its Effect on Pro‐Inflammatory Pathways and Calcium Influx in Prostate Cancer
por: Al‐Bakheit, Ala'a, et al.
Publicado: (2016)

Aqueous Extract of Glucoraphanin-Rich Broccoli Sprouts Inhibits Formation of Advanced Glycation End Products and Attenuates Inflammatory Reactions in Endothelial Cells
por: Sotokawauchi, Ami, et al.
Publicado: (2018)

Enhanced production of sulforaphane by exogenous glucoraphanin hydrolysis catalyzed by myrosinase extracted from Chinese flowering cabbage (Brassica rapa var. parachinensis)
por: Sangkret, Supakarn, et al.
Publicado: (2019)

Broccoli-Derived Glucoraphanin Activates AMPK/PGC1α/NRF2 Pathway and Ameliorates Dextran-Sulphate-Sodium-Induced Colitis in Mice
por: Tian, Qiyu, et al.
Publicado: (2022)

Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate
por: Traka, Maria, et al.
Publicado: (2008)

Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial
por: Satomi, Shohei, et al.
Publicado: (2022)

The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer
por: Traka, Maria H, et al.
Publicado: (2010)

Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation
por: Matsuura, Akiko, et al.
Publicado: (2018)

Beneficial Effect of H(2)S-Releasing Molecules in an In Vitro Model of Sarcopenia: Relevance of Glucoraphanin
por: Micheli, Laura, et al.
Publicado: (2022)

Comparative bio-accessibility, bioavailability and bioequivalence of quercetin, apigenin, glucoraphanin and carotenoids from freeze-dried vegetables incorporated into a baked snack versus minimally processed vegetables: Evidence from in vitro models and a human bioavailability study
por: Perez-Moral, Natalia, et al.
Publicado: (2018)

Biofortification of oilseed Brassica juncea with the anti-cancer compound glucoraphanin by suppressing GSL-ALK gene family
por: Augustine, Rehna, et al.
Publicado: (2015)

Dietary intake of glucoraphanin prevents the reduction of dopamine transporter in the mouse striatum after repeated administration of MPTP
por: Pu, Yaoyu, et al.
Publicado: (2019)

Development of a LC-MS/MS Method for the Simultaneous Detection of Tricarboxylic Acid Cycle Intermediates in a Range of Biological Matrices
por: Al Kadhi, Omar, et al.
Publicado: (2017)

Accumulation of Sulforaphane and Alliin in Human Prostate Tissue
por: Livingstone, Tracey L., et al.
Publicado: (2022)

Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice
por: Yao, Wei, et al.
Publicado: (2016)

Dietary intake of glucoraphanin during pregnancy and lactation prevents the behavioral abnormalities in the offspring after maternal immune activation
por: Fujita, Yuko, et al.
Publicado: (2020)

Glucoraphanin Triggers Rapid Antidepressant Responses in a Rat Model of Beta Amyloid-Induced Depressive-like Behaviour
por: Tucci, Paolo, et al.
Publicado: (2022)

Sulforaphane rewires central metabolism to support antioxidant response and achieve glucose homeostasis
por: Bernuzzi, Federico, et al.
Publicado: (2023)

Characterisation of the Introgression of Brassica villosa Genome Into Broccoli to Enhance Methionine-Derived Glucosinolates and Associated Health Benefits
por: Neequaye, Mikhaela, et al.
Publicado: (2022)

Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction
por: Xu, Liang, et al.
Publicado: (2019)

Glucoraphanin Increases Intracellular Hydrogen Sulfide (H(2)S) Levels and Stimulates Osteogenic Differentiation in Human Mesenchymal Stromal Cell
por: Gambari, Laura, et al.
Publicado: (2022)

A Physiological-Based Model for Simulating the Bioavailability and Kinetics of Sulforaphane from Broccoli Products
por: Shekarri, Quchat, et al.
Publicado: (2021)

Sulforaphane Bioavailability in Healthy Subjects Fed a Single Serving of Fresh Broccoli Microgreens
por: Bouranis, John A., et al.
Publicado: (2023)

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?
por: Yagishita, Yoko, et al.
Publicado: (2019)

Molecular Cloning, Expression Pattern and Genotypic Effects on Glucoraphanin Biosynthetic Related Genes in Chinese Kale (Brassica oleracea var. alboglabra Bailey)
por: Yin, Ling, et al.
Publicado: (2015)

Enriching Glucoraphanin in Brassica rapa Through Replacement of BrAOP2.2/BrAOP2.3 with Non-functional Genes
por: Liu, Zhiyuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lr2fu5m340pljl93nnh9qk1uuj