Maintenance dose conversion between oral risperidone and paliperidone palmitate 1 month: Practical guidance based on pharmacokinetic simulations

AIM: We assessed the dosage strengths of paliperidone palmitate 1‐month (PP1M) long‐acting injectable resulting in similar steady‐state (SS) exposures to the dosage strengths of oral risperidone using pharmacokinetic (PK) simulations. METHODS: Population PK simulations of SS PK were performed using...

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Detalles Bibliográficos
Autores principales: Russu, Alberto, Kern Sliwa, Jennifer, Ravenstijn, Paulien, Singh, Arun, Mathews, Maju, Kim, Edward, Gopal, Srihari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175146/
https://www.ncbi.nlm.nih.gov/pubmed/29707876
http://dx.doi.org/10.1111/ijcp.13089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175146/
https://www.ncbi.nlm.nih.gov/pubmed/29707876
http://dx.doi.org/10.1111/ijcp.13089

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