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Blinded and unblinded sample size reestimation in crossover trials balanced for period
The determination of the sample size required by a crossover trial typically depends on the specification of one or more variance components. Uncertainty about the value of these parameters at the design stage means that there is often a risk a trial may be under‐ or overpowered. For many study desi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175184/ https://www.ncbi.nlm.nih.gov/pubmed/30073679 http://dx.doi.org/10.1002/bimj.201700092 |