Evaluation of Eluxadoline Effect on Cardiac Repolarization

This study evaluated the effects of eluxadoline, a mixed μ‐opioid receptor (OR) and κ‐OR agonist and δ‐OR antagonist, on cardiac repolarization. This evaluator‐blinded, placebo‐ and positive‐controlled, 4‐period crossover study randomized healthy men and women to single oral doses of eluxadoline (th...

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Detalles Bibliográficos
Autores principales: Bonifacio, Laura, Hunt, Thomas L., McIntyre, Gail, Dove, Leonard S., Covington, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175186/
https://www.ncbi.nlm.nih.gov/pubmed/29659201
http://dx.doi.org/10.1002/cpdd.453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175186/
https://www.ncbi.nlm.nih.gov/pubmed/29659201
http://dx.doi.org/10.1002/cpdd.453

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