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Evaluation of Eluxadoline Effect on Cardiac Repolarization
This study evaluated the effects of eluxadoline, a mixed μ‐opioid receptor (OR) and κ‐OR agonist and δ‐OR antagonist, on cardiac repolarization. This evaluator‐blinded, placebo‐ and positive‐controlled, 4‐period crossover study randomized healthy men and women to single oral doses of eluxadoline (th...
Autores principales: | Bonifacio, Laura, Hunt, Thomas L., McIntyre, Gail, Dove, Leonard S., Covington, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175186/ https://www.ncbi.nlm.nih.gov/pubmed/29659201 http://dx.doi.org/10.1002/cpdd.453 |
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