A characterization of postzygotic mutations identified in monozygotic twins

Postzygotic mutations are DNA changes acquired from the zygote stage onwards throughout the lifespan. These changes lead to differences in DNA sequence among cells of an individual, potentially contributing to the etiology of complex disorders. Here we compared whole genome DNA sequence data of two...

Descripción completa

Detalles Bibliográficos
Autores principales: Ouwens, Klaasjan G., Jansen, Rick, Tolhuis, Bas, Slagboom, P. Eline, Penninx, Brenda W.J.H., Boomsma, Dorret I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175188/
https://www.ncbi.nlm.nih.gov/pubmed/29980163
http://dx.doi.org/10.1002/humu.23586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175188/
https://www.ncbi.nlm.nih.gov/pubmed/29980163
http://dx.doi.org/10.1002/humu.23586

Ejemplares similares