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Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number of studies have demonstrated functionality of DA neurons originating from hESCs when grafted to the striatum of rode...

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Detalles Bibliográficos
Autores principales: Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175216/
https://www.ncbi.nlm.nih.gov/pubmed/30007046
http://dx.doi.org/10.1002/cne.24500