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Population Pharmacokinetics and Pharmacodynamics of Oral Propranolol in Pediatric Patients With Infantile Hemangioma

This study aimed to characterize the population pharmacokinetics and exposure‐response relationship of propranolol (Hemangiol(®) Syrup for Pediatric) in infants with infantile hemangioma. Using nonlinear mixed‐effects modeling with 63 pooled sets of plasma concentration‐time data from 32 Japanese pa...

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Detalles Bibliográficos
Autores principales: Takechi, Tomoki, Kumokawa, Tadao, Kato, Rumiko, Higuchi, Takeshi, Kaneko, Tsuyoshi, Ieiri, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175224/
https://www.ncbi.nlm.nih.gov/pubmed/29746707
http://dx.doi.org/10.1002/jcph.1149