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Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer

Intratumor heterogeneity is increasingly recognized as a major factor impacting diagnosis and personalized treatment of cancer. We characterized stochastic phenotype switching as a mechanism contributing to intratumor heterogeneity and malignant potential of liver cancer. Clonal analysis of primary...

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Detalles Bibliográficos
Autores principales: Matak, Andrija, Lahiri, Pooja, Ford, Ethan, Pabst, Daniela, Kashofer, Karl, Stellas, Dimitris, Thanos, Dimitris, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175233/
https://www.ncbi.nlm.nih.gov/pubmed/29171037
http://dx.doi.org/10.1002/hep.29679