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Electrostatic recognition in substrate binding to serine proteases

Serine proteases of the Chymotrypsin family are structurally very similar but have very different substrate preferences. This study investigates a set of 9 different proteases of this family comprising proteases that prefer substrates containing positively charged amino acids, negatively charged ami...

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Detalles Bibliográficos
Autores principales: Waldner, Birgit J., Kraml, Johannes, Kahler, Ursula, Spinn, Alexander, Schauperl, Michael, Podewitz, Maren, Fuchs, Julian E., Cruciani, Gabriele, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175425/
https://www.ncbi.nlm.nih.gov/pubmed/29785722
http://dx.doi.org/10.1002/jmr.2727