Top‐down and bottom‐up characterization of nitrated birch pollen allergen Bet v 1a with CZE hyphenated to an Orbitrap mass spectrometer

Tyrosine (Tyr) residues of the major pollen allergen of birch Betula verrucosa, Bet v 1a, were nitrated by peroxynitrite. This modification enhances the allergenicity. Modified tyrosines were identified by analyzing intact allergen variants in combination with top‐down and bottom‐up approaches. Ther...

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Detalles Bibliográficos
Autores principales: Gusenkov, Sergey, Stutz, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Part II. CE‐MS and LC‐MS Bioanalytical Application
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175448/
https://www.ncbi.nlm.nih.gov/pubmed/29389018
http://dx.doi.org/10.1002/elps.201700413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175448/
https://www.ncbi.nlm.nih.gov/pubmed/29389018
http://dx.doi.org/10.1002/elps.201700413

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