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1H-1,2,3-Triazole Tethered Nitroimidazole–Isatin Conjugates: Synthesis, Docking, and Anti-Proliferative Evaluation against Breast Cancer

[Image: see text] 1H-1,2,3-Triazole tethered imidazole–isatin and imidazole–isatin–thiosemicarbazone conjugates were synthesized and evaluated against MCF-7 and MDA-MB-231 cell lines. Antiproliferative activities of the synthesized conjugates revealed an optimum combination of longer alkyl chain len...

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Detalles Bibliográficos
Autores principales: Kumar, Sumit, Saha, Sourav Taru, Gu, Liang, Palma, Gabriella, Perumal, Shanen, Singh-Pillay, Ashona, Singh, Parvesh, Anand, Amit, Kaur, Mandeep, Kumar, Vipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175498/
https://www.ncbi.nlm.nih.gov/pubmed/30320289
http://dx.doi.org/10.1021/acsomega.8b01513