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RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides

The function of Toll pathway defense against bacterial infection has been well established in shrimp, however how this pathway responds to viral infection is still largely unknown. In this study, we report the Toll4-Dorsal-AMPs cascade restricts the white spot syndrome virus (WSSV) infection of shri...

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Detalles Bibliográficos
Autores principales: Li, Haoyang, Yin, Bin, Wang, Sheng, Fu, Qihui, Xiao, Bang, Lǚ, Kai, He, Jianguo, Li, Chaozheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175524/
https://www.ncbi.nlm.nih.gov/pubmed/30256850
http://dx.doi.org/10.1371/journal.ppat.1007109